Killer Instinct

Killer Instinct can refer to:
 * Killer Instinct (series): The fighting video game franchise.
 * Killer Instinct (1994): The first game in the series, released for arcades and the Super Nintendo Entertainment System.
 * Killer Instinct (Game Boy): A version of the first Killer Instinct video game released in 1995.
 * Killer Instinct (2013): The 2013 reboot of the Killer Instinct franchise, released for Xbox One and Microsoft Windows.
 * Killer Instinct (2021 arcade cabinet): An arcade machine made by Arcade 1Up that includes the first two Killer Instinct video games, along with three Battletoads video games.
 * Killer Instinct (comic book series): A series of comic books that first started in 1996.